In the hematology department, there are many patients with thrombocytopenia, whose condition is long-term cure and repeated, which brings great harm to daily life, physical and mental physiology and life; but at the same time, there are also some patients with thrombocytopenia, which has a good therapeutic effect, and platelets quickly return to normal range.
The common cause of thrombocytopenia is the imbalance of the patient's autoimmune function, resulting in excessive production of anti-platelet antibodies in the body, resulting in platelet destruction or excessive consumption. And HIV infection or systemic lupus erythematosus, Sjogren's syndrome and other immune diseases, can be accompanied by thrombocytopenia. In some cases, tumors are also associated with thrombocytopenia.
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Antiplatelet antibody level
Antiplatelet antibody test was positive in most patients, and the range was slightly less than that in patients with negative results. Antiplatelet antibody is considered to be the main factor related to the diagnosis of ITP. The disorder of humoral immune response is due to the complex interaction between antigen cells and lymphocyte T and B, and platelet is the antigen presenting cell.
Identification of hepatitis B virus surface antigen (AgHBs)
The determination of HBV antigen emphasizes HBV surface antigen. The presence of AgHBs in human plasma/serum indicates that HBV has been infected. Only a few patients were positive for AgHBs. The average PC value of these patients was slightly higher, but there was no significant difference compared with the negative patients.
Anti-hepatitis C virus (HCV) antibody test
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