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  • 血小板减少与自身哪些免疫性疾病和病毒有关

    来源:www.cecemca.com 发布时间:2019-10-09

    In the hematology department, there are many patients with thrombocytopenia, whose condition is long-term cure and repeated, which brings great harm to daily life, physical and mental physiology and life; but at the same time, there are also some patients with thrombocytopenia, which has a good therapeutic effect, and platelets quickly return to normal range.

    The common cause of thrombocytopenia is the imbalance of the patient's autoimmune function, resulting in excessive production of anti-platelet antibodies in the body, resulting in platelet destruction or excessive consumption. And HIV infection or systemic lupus erythematosus, Sjogren's syndrome and other immune diseases, can be accompanied by thrombocytopenia. In some cases, tumors are also associated with thrombocytopenia.

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    Antiplatelet antibody level

    Antiplatelet antibody test was positive in most patients, and the range was slightly less than that in patients with negative results. Antiplatelet antibody is considered to be the main factor related to the diagnosis of ITP. The disorder of humoral immune response is due to the complex interaction between antigen cells and lymphocyte T and B, and platelet is the antigen presenting cell.

    Identification of hepatitis B virus surface antigen (AgHBs)

    The determination of HBV antigen emphasizes HBV surface antigen. The presence of AgHBs in human plasma/serum indicates that HBV has been infected. Only a few patients were positive for AgHBs. The average PC value of these patients was slightly higher, but there was no significant difference compared with the negative patients.

    Anti-hepatitis C virus (HCV) antibody test

    与丙型肝炎病毒不同的免疫球蛋白g(igg)抗体产生的证据。丙型肝炎病毒有六种主要基因型和50种血清型。试验表明,这6个基因型的高灵敏度来自不同地理区域的人群。了解基因型和血清型非常有用。

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    hiv抗体水平

    在hiv阳性患者中,pc值较低,血小板减少源于itp。巨细胞感染和艾滋病也可能导致血小板减少。艾滋病合并itp患者也可能由机会性感染、恶性疾病或某些药物(化疗、干扰素和抗病毒药物)引起。

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